Cyanide poisoning treatment

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Revision as of 01:36, 4 December 2024 by Admin (talk | contribs) (Created page with "__TOC__ ==Causes== * Exposure to sodium cyanide, potassium cyanide, or hydrogen cyanide. ==Symptomology== Confusion from hypoxia and muscle pain from lactic acid buildup. Low blood oxygen, low blood pH. ==Treatment== * Supplemental Oxygen, '''and''' * IM or IV sodium thiosulfate '''and''' * one, but '''not''' both of ** IM or IV sodium nitrite '''--or--''' ** IM or IV hydroxocobalamin ===Warnings=== * Do '''not''' co-administer hydroxocobalam...")
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Causes

Symptomology

Confusion from hypoxia and muscle pain from lactic acid buildup. Low blood oxygen, low blood pH.

Treatment

Warnings

  • Do not co-administer hydroxocobalamin and nitrite.

Dosage

  • Sodium nitrite: 300 mg intravenously (IV) at a rate of 25% to 50% perminute. IM is an acceptable alternative to IV.
  • Sodium thiosulfate: 12.5 grams, slow IV. IM is an acceptable alternative to IV.
  • Hydroxocobalamin 70 mg/kg (usually 5 g) IV infusion over 15 minutes; additional 5 g IV may be given depending on severity of poisoning and clinical response. Not to exceed a cumulative dose of 10 g. IM is an acceptable alternative to IV