6-APA
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| |
| Chemical formula | C8H12N2O3S |
|---|---|
| OTP appearance | white solid |
| Molar Mass(g/mol) | 216.257 |
| Melting Point(°C) | 198 |
| Boiling Point(°C) | 207(decomp) |
| Solubility in water(g/L) | 4 |
| NFPA 704 |  0
0
0
|
Uses
Primary
- Key intermediate in the production of synthetic penicillins
Natural occurrence
- Does occur naturally in secondary metabolites of penicillium chrysogenum
Hazards
Production
Extraction
From a fermentation broth of penicillium chrysogenum, extract 6-APA[1]
Synthesis
- From Penicillin G[2][3]
Purification
Storage
Disposal
See Also
References
- ↑ US patent 2941995 "Recovery of solid 6-aminopenicillanic acid"
Link courtesy Google - ↑ US patent 3509168 "Process for extracting 6-aminopenicillanic acid for production of penicillins"
Link courtesy Google - ↑ US patent 3929767 "Process of producing semi-synthetic penicillin"
Link courtesy Google