Chlorhexidine

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Chlorhexidine
Chemical formula C22H30Cl2N10
Molar Mass(g/mol) 505.446 
Solubility in water(g/L) 0.0008
NFPA 704
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Uses

Primary

  • Pharm: WHO LEM antiseptic

Natural occurrence

  • Does not occur naturally

Hazards

Production

Synthesis

The product is built from butadiene outwards, through 1,6-diaminohexane and then:

  1. React 1,6-diaminohexane with 2-cyanoguanidine to produce hexamethylene - bis cyanoguanidine
  2. React hexamethylene - bis cyanoguanidine with 4-chloroaniline to produce chlorhexidine[1]

Testing

Purification

Storage

Disposal

See Also

References

  1. US patent 2684924 "N-Chlorophenyldiguanidino Compounds"
    Link courtesy Google