Metformin

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Metformin
Chemical formula C4H11N5
Molar Mass(g/mol) 129.16364
NFPA 704
NFPA704.png
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Uses

Primary

  • Pharm: WHO LEM component

Natural occurrence

Hazards

Production

Extraction

Synthesis

  1. Produce dimethylamine hydrochloride
    1. Neutralize dimethylamine with hydrochloric acid:
      NH(CH3)2 + HCl → NH2(CH3)2Cl
  2. React dimethylamine hydrochloride and 2-cyanoguanidine over heat
    NH2(CH3)2Cl + C2H4N4
    {
    →
    heat}
    C4H11N5 + HCl

Testing

Purification

Storage

Disposal

See Also

References

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