4-aminobenzoic acid

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Revision as of 22:51, 2 December 2024 by Admin (talk | contribs) (Created page with "{{Compound|struct=PABA.png|chemf=C7H7NO2|mm=137.14|density=1.374|mp=186.5|bp=340|sol_aq=5.882|stp_p=crystals|stp_q=grey-white|nfpa_h=1|nfpa_f=1}} :aka PABA, ParaAminoBenzoicAcid ==Uses== ===Primary=== * Feedstock for WHO LEM items benzocaine and procaine ==Natural occurrence== * '''Does''' occur naturally in many bacteria in order to produce folic acid or folate. ==Hazards== ==Production== ===Extraction=== ===Synthesis=== # Reduce 4-nitrobenzoic acid with...")
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4-aminobenzoic acid
Chemical formula C7H7NO2
OTP appearance grey-white crystals 
Molar Mass(g/mol) 137.14 
Density(g/cc) 1.374 
Melting Point(°C) 186.5 
Boiling Point(°C) 340 
Solubility in water(g/L) 5.882
NFPA 704
NFPA704.png
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aka PABA, ParaAminoBenzoicAcid

Uses

Primary

Natural occurrence

  • Does occur naturally in many bacteria in order to produce folic acid or folate.

Hazards

Production

Extraction

Synthesis

  1. Reduce 4-nitrobenzoic acid with tin and hydrochloric acid (Zinin)
    C7H5NO4(aq) + 3 Sn + 6 HCl
    {
    →
    115deg;C, 20 min}
    C7H7NO2(aq) + 3 SnCl2 + 2 H2O
  2. filter
  3. wash with water
  4. discard residue (tin and tin chloride)
  5. Neutralize with ammonia
  6. warm the solution
  7. filter
  8. evaporate solution
  9. retain residue of 4-aminobenzoic acid

Purification

Recrystllize from 25% ethanol solution

Storage

Disposal

See Also

References

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