Bupivacaine

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Revision as of 19:28, 3 December 2024 by Admin (talk | contribs) (Created page with "{{Compound |chemf=C18H28N2O|struct=Bupivicaine.png|mm=288.43|density=|mp=107-108°C |medicine=yes |medication=yes|listed_who=yes|listed_dhs=yes}} ==Uses== ===Primary=== * Pharm: WHO LEM local anesthetics ==Natural occurrence== ==Hazards== ==Production== ===Extraction=== ===Synthesis=== * See patent WO 2009089842A1<ref>{{cite web|url=https://patents.google.com/patent/WO2009089842A1/en|title=WO 2009089842A1|courtesy=Google Patents}}</ref> * See diagram from wikimedia co...")
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Bupivacaine
Chemical formula C18H28N2O
Molar Mass(g/mol) 288.43 
Melting Point(°C) 107-108°C
NFPA 704
NFPA704.png
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Uses

Primary

  • Pharm: WHO LEM local anesthetics

Natural occurrence

Hazards

Production

Extraction

Synthesis

  • See patent WO 2009089842A1[1]
  • See diagram from wikimedia commons[2]
  1. Combine Picolininc acid and ethyl chloroformate in the presence of a base
  2. Add 2,6-Xylidine
  3. Add N-butyl iodide
  4. Reduce with hydrogen

Testing

Purification

Storage

Disposal

See Also

References

  1. ↑ WO 2009089842A1
    courtesy Google Patents.
  2. ↑ Bupivicain Synthesis
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